Windows viruses do not run in Wine. Some of them may cause crashes, but that's all, no actual security risk. People keep forgetting viruses exploit software vulnerabilities, you don't expect non-MS Wine system have the same vulnerabilities as MS Windows, do you?
I use clamav occasionally to scan my home. Sometimes there are some found in my browser cache. No wonder, I do not restrict my browsing like scared Windows users do. Nevertheless, none of that stuff found there can do any damage in Linux.

Actually there are options you can add to xorg.conf.d, what these options exactly look like depends on driver used. And all that what you did with xrandr can be added to conf file(s), too.

Yea, as promised systemd is fully modular and anyone can choose what functionality they want ... oh wait ...

Instead of UID you can use file system labels. Much nicer, if you ask me. And one can memorize labels ... some maybe can memorize UID-s ... LOL

There is one step what may be failing, after UEFI GRUB is installed its EFI binary must be "introduced" to the EFI BIOS. If this step fails then you get this error. Presuming there are no other EFI binaries.
I'd boot from an external media and check if GRUB binary is present somewhere in ../boot/efi/. If it is then copying it to ../boot/efi/bootx64.efi will make your system bootable, this is the default location by UEFI standard and the executable there is found without registering it with UEFI BIOS beforehand.

P. S. You absolutely sure your computer has UEFI BIOS?

What's the big idea using nVidia blob with this old card. Use nouveau or Xorg modesetting driver. My laptop has newer card than yours, I tested it with blob and nouveau and modesetting and for 2D applications there is no difference, actually FOSS drivers are snappier.
Note, no FOSS Xorg driver will run if you pass nomodesetting to your kernel.