We have a bout 50 systems in our shop. 
Currently we are using Win 10, SL 6.5 and Sl 7.5. and one Devuan 4.0

Since RH has been IBM-d we plan to update all systems to Devuan.  The two test boxes have been running for about a year.  We can run all of our cad packages and everything works.
The only hard part is to setup users.   We maintain all users with a unique USID over all systems.   So if you need anything just set down to a box and login.
and you have acess to your account and the server.

SL 6.5 uses a dialog that allows you assign a user name, USID, and group.   Shamelessly copy it and add it Devuan

The test box is running an 8 core AMD with 32 G of ram and 4 T Byte disks with a SSD for the OS.  Incredible performance.
Cad Packages we run:
VariCad
Eagle
Spice
Several in house simulations with random access I/O of variables.
VMWare 17:
      NT 2000 so we can access our old autocad files in orrig. format.
      DOs
      Win 7
      Win 10
These are used to support projects from the last 24 years.
What we do is design and build custom embedded system.  Software and hardware.

I am one of those  condesending UNIX user accprding tp Dilbert.

I would also like to make a donation.  Send infol.

We were ready to can a Toshiba 32 bit laptop.  We installed a 1 TB ssd and Devuan and it really came to life.  Runs 32 bit versions of our cad packages with out a problem.  Save us a log of $$ on new laptops.  Just breaks my heart to see investments of 100 or $ put in trash pile.

Thank You
ljlinde