As I have first-hand experience with Linux and 2-in-1 laptops, I think it might be useful to say a few words about my experiences.

I am currently using a trusty ThinkPad X201 Tablet (i7, 8 GB RAM, 1 TB SSD, WWAN, etc.) with Debian Buster (since Devuan Ascii/Debian Stretch still has this unfixed bug) and KDE Plasma Desktop. I am using the digitizer daily for note-taking and it works perfectly fine. In general this notebook is fully compatible with Linux. I have connected an AMD Sapphire RX560 eGPU via ExpressCard at home, to play some games in my free time (of course I am playing games that are running natively under Linux: SCS Software). This makes the X201 Tablet extremely flexible for every use-case I could think of.

Before switching to the X201 Tablet, I used several ThinkPad X230 Tablets, which I all sold, since they were way too fragile (there was always some plastic part breaking or some new spot in the LC display). In-between all those X230 Tablets I had several of the newer ThinkPad Yoga 14/460/370 devices. They all had some kind of defect (each of these new Yogas was sent in multiple times for repair right after getting it!). Anything newer than the Yoga 460 has a fingerprint reader that doesn't work with Linux, but besides that, everything - including the Wacom AES digitizer - worked fine with Linux (Debian Buster).
The Wacom AES digitzer has some issues in combination with VirtualBox though, so I wouldn't recommend it, if you are using Windows-only software for note-taking. For that I would recommend the older Wacom EMR digitizer, which most older convertibles and the current Fujitsu Lifebook T-series have.
I sold my ThinkPad Yoga laptops, since I got headaches while using them (probably caused by PWM dimming), they were way too fragile for daily useage and the issues with Wacom AES and VirtualBox were a major issue for my workflow.

For a very short time I also tried a Dell Venue 11 Pro out (I believe it had one of these "always on" Bay Trail Atom CPUs). This didn't work properly with Linux at all:
- I couldn't use the Synaptics digitizer, since it was unsupported by many programs (e. g. Xournal) and the active Dell pen drained the internal pen battery within two weeks (used it for a while with Windows), so keeping the pen alive was extremely expensive (AAAA batteries aren't exactly cheap ...)
- I couldn't decrypt the device, as there was no virtual keyboard available at the boot screen
- I couldn't unlock the device, since KDE decided at that time that a virtual keyboard on the new KDE 5 lockscreen wasn't all that important
- I couldn't put the tablet to sleep, since the Bay Trail sleep states were unsupported
- I believe WLAN didn't work either?
- ...
Besides all these negative aspects, there were some nice touches I encountered while using it with Windows: The Synaptics digitizer made my handwriting look natural (very smooth curves!) and battery life was amazing! Performance was sufficient for basic OneNote writing, but saving PDFs with PDF Annotator took quite a while.

That brings me to the software-side of things:
- As far as PDF annotating goes (I use checked ISO 216 A4 PDFs for writing), there is simply no useable software for Linux available. I use PDF Annotator for that, which I have installed in a stripped-down virtual machine with Windows 10.
- As far as painting/drawing/photo editing goes, there is for example Krita. It has great stylus support (with pressure sensitivity) and I can very much recommend it as a replacement for Photoshop/GIMP (and darktable as a perfect Lightroom replacement).

I hope this quick writeup helps you with your decision a bit. If you have any questions, feel free to ask.